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Innate Killing of Leishmania donovani by Macrophages of the Splenic Marginal Zone Requires IRF-7

Highly phagocytic macrophages line the marginal zone (MZ) of the spleen and the lymph node subcapsular sinus. Although these macrophages have been attributed with a variety of functions, including the uptake and clearance of blood and lymph-borne pathogens, little is known about the effector mechani...

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Autors principals: Phillips, Rebecca, Svensson, Mattias, Aziz, Naveed, Maroof, Asher, Brown, Najmeeyah, Beattie, Lynette, Signoret, Nathalie, Kaye, Paul M.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837405/
https://ncbi.nlm.nih.gov/pubmed/20300600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000813
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