Effects of Transcriptional Pausing on Gene Expression Dynamics

Stochasticity in gene expression affects many cellular processes and is a source of phenotypic diversity between genetically identical individuals. Events in elongation, particularly RNA polymerase pausing, are a source of this noise. Since the rate and duration of pausing are sequence-dependent, th...

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Bibliographic Details
Main Authors: Rajala, Tiina, Häkkinen, Antti, Healy, Shannon, Yli-Harja, Olli, Ribeiro, Andre S.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837387/
https://ncbi.nlm.nih.gov/pubmed/20300642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1000704
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