Llwytho...

An RNAi screen identifies metabolic regulators NR1D1 and PBP as novel survival factors for breast cancer cells with the ERBB2 signature

Overexpression of the adverse prognostic marker ERBB2 occurs in 30% of breast cancers, however, therapies targeting this gene have not proven to be as effective as was initially hoped. Transcriptional profiling meta-analyses have shown that there are approximately 150 genes co-overexpressed with ERB...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kourtidis, Antonis, Jain, Ritu, Carkner, Richard D., Eifert, Cheryl, Brosnan, M. Julia, Conklin, Douglas S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837372/
https://ncbi.nlm.nih.gov/pubmed/20160030
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-09-1550
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