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TGF-β Isoform Specific Regulation of Airway Inflammation and Remodelling in a Murine Model of Asthma

The TGF-β family of mediators are thought to play important roles in the regulation of inflammation and airway remodelling in asthma. All three mammalian isoforms of TGF-β, TGF-β(1–3), are expressed in the airways and TGF-β(1) and -β(2) are increased in asthma. However, there is little information o...

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Detalhes bibliográficos
Main Authors: Bottoms, Stephen E., Howell, Jane E., Reinhardt, Alistair K., Evans, Iona C., McAnulty, Robin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837347/
https://ncbi.nlm.nih.gov/pubmed/20300191
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009674
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