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Plasmacytoid dendritic cell–derived type I interferon is crucial for the adjuvant activity of Toll-like receptor 7 agonists

There is a high demand for the development of adjuvants that induce cytotoxic T lymphocytes, which are crucial for the elimination of intracellular pathogens and tumor cells. Toll-like receptor (TLR) agonists are prime candidates to fulfill this role because they induce innate immune activation and...

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Bibliografiske detaljer
Main Authors: Rajagopal, Deepa, Paturel, Carine, Morel, Yannis, Uematsu, Satoshi, Akira, Shizuo, Diebold, Sandra S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Hematology 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837337/
https://ncbi.nlm.nih.gov/pubmed/20065291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-238543
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