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Allogeneic T regulatory cell–mediated transplantation tolerance in adoptive therapy depends on dominant peripheral suppression and central tolerance
T regulatory cells (Tregs) represent agents to mediate tolerance to allografts so that the use of immunosuppressive drugs is avoided. In this regard, we previously demonstrated that the adoptive transfer of allogeneic Tregs into IL-2Rβ(−/−) mice prevented autoimmunity and led to allograft tolerance....
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837323/ https://ncbi.nlm.nih.gov/pubmed/20040758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-08-238584 |
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