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HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy
Autophagy is primarily considered a non-selective degradation process induced by starvation. Nutrient-independent basal autophagy, in contrast, imposes intracellular QC by selective disposal of aberrant protein aggregates and damaged organelles, a process critical for suppressing neurodegenerative d...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837169/ https://ncbi.nlm.nih.gov/pubmed/20075865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.405 |
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