HDAC6 controls autophagosome maturation essential for ubiquitin-selective quality-control autophagy

Autophagy is primarily considered a non-selective degradation process induced by starvation. Nutrient-independent basal autophagy, in contrast, imposes intracellular QC by selective disposal of aberrant protein aggregates and damaged organelles, a process critical for suppressing neurodegenerative d...

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Detalhes bibliográficos
Principais autores: Lee, Joo-Yong, Koga, Hiroshi, Kawaguchi, Yoshiharu, Tang, Waixing, Wong, Esther, Gao, Ya-Sheng, Pandey, Udai B, Kaushik, Susmita, Tresse, Emily, Lu, Jianrong, Taylor, J Paul, Cuervo, Ana Maria, Yao, Tso-Pang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837169/
https://ncbi.nlm.nih.gov/pubmed/20075865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.405
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