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Extending the transposable payload limit of Sleeping Beauty (SB) using the Herpes Simplex Virus (HSV)/SB amplicon vector platform
The ability of a viral vector to safely deliver and stably integrate large transgene units (transgenons), which not only include one or several therapeutic genes but also requisite native transcriptional regulatory elements, would be of significant benefit for diseases presently refractory to availa...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2009
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837128/ https://ncbi.nlm.nih.gov/pubmed/19865178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2009.144 |
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