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The IGF-1/IGF-1R signaling axis in the skin: a new role for the dermis in aging-associated skin cancer
The appropriate response of human keratinocytes to UVB is dependent on the activation status of the IGF-1 receptor. Keratinocytes grown in conditions where the IGF-1 receptor is inactive, inappropriately replicate in the presence of UVB-induced DNA damage. In human skin epidermal keratinocytes do no...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2837099/ https://ncbi.nlm.nih.gov/pubmed/19966862 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.440 |
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