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The Effect of Variation in Expression of the Candidate Dyslexia Susceptibility Gene Homolog Kiaa0319 on Neuronal Migration and Dendritic Morphology in the Rat

We investigated the postnatal effects of embryonic knockdown and overexpression of the candidate dyslexia gene homolog Kiaa0319. We used in utero electroporation to transfect cells in E15/16 rat neocortical ventricular zone with either 1) small hairpin RNA (shRNA) vectors targeting Kiaa0319, 2) a KI...

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Detalhes bibliográficos
Main Authors: Peschansky, Veronica J., Burbridge, Timothy J., Volz, Amy J., Fiondella, Christopher, Wissner-Gross, Zach, Galaburda, Albert M., Turco, Joseph J. Lo, Rosen, Glenn D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837091/
https://ncbi.nlm.nih.gov/pubmed/19679544
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cercor/bhp154
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