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Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison

BACKGROUND: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represented as sequence profiles is arguably the most effective homology detection strategy. However, finding the best way to repr...

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Detalhes bibliográficos
Main Authors: Margelevičius, Mindaugas, Venclovas, Česlovas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837030/
https://ncbi.nlm.nih.gov/pubmed/20158924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-89
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