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Detection of distant evolutionary relationships between protein families using theory of sequence profile-profile comparison

BACKGROUND: Detection of common evolutionary origin (homology) is a primary means of inferring protein structure and function. At present, comparison of protein families represented as sequence profiles is arguably the most effective homology detection strategy. However, finding the best way to repr...

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Hlavní autoři: Margelevičius, Mindaugas, Venclovas, Česlovas
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2837030/
https://ncbi.nlm.nih.gov/pubmed/20158924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-89
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