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Nerve growth factor deprivation results in the reactivation of latent herpes simplex virus in vitro.

Primary sympathetic neuronal cultures were maintained for up to 5 weeks after inoculation with herpes simplex virus (HSV) without evidence of viral infection. Upon deprivation of nerve growth factor, the cultures produced infectious HSV, indicating that the cultures harbored latent HSV. This study d...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Wilcox, C L, Johnson, E M
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283698/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3035230/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.7.2311-2315.1987
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