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Heterotrimeric G-Proteins Interact Directly with Cytoskeletal Components to Modify Microtubule-Dependent Cellular Processes

A large percentage of current drugs target G-protein-coupled receptors, which couple to well-known signaling pathways involving cAMP or calcium. G-proteins themselves may subserve a second messenger function. Here, we review the role of tubulin and microtubules in directly mediating effects of heter...

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Detalhes bibliográficos
Main Authors: Dave, Rahul H., Saengsawang, Witchuda, Yu, Jiang-Zhou, Donati, Robert, Rasenick, Mark M.
Formato: Artigo
Idioma:Inglês
Publicado em: S. Karger AG 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836952/
https://ncbi.nlm.nih.gov/pubmed/19212143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000186693
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