Human papillomavirus type 16 E6 increases the degradation rate of p53 in human keratinocytes.
The E6 proteins of the high-risk human papillomaviruses (HPVs) have been shown to form a complex with and induce the degradation of human p53 in vitro. To determine whether p53 is degraded more rapidly in cells expressing E6 in vivo, the half-life of p53 was determined by pulse-chase analysis in ear...
Guardado en:
| Publicado en: | J Virol |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Microbiology (ASM)
1992
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283680/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1326671/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.10.6237-6241.1992 |
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