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Suppression of conditioning to ambiguous cues by pharmacogenetic inhibition of the dentate gyrus
Serotonin receptor 1A knockout (Htr1a(KO)) mice show increased anxiety-related behavior in tests measuring innate avoidance. Here we demonstrate that Htr1a(KO) mice show enhanced fear conditioning to ambiguous conditioned stimuli, a hallmark of human anxiety. To examine the involvement of specific f...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836794/ https://ncbi.nlm.nih.gov/pubmed/17558402 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn1919 |
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