Construction of a High Resolution Linkage Disequilibrium Map to Evaluate Common Genetic Variation in TP53 and Neural Tube Defect Risk in an Irish Population

Genetic and environmental factors contribute to the etiology of neural tube defects (NTDs). While periconceptional folic acid supplementation is known to significantly reduce the risk of NTDs, folate metabolic pathway related factors do not account for all NTDs. Evidence from mouse models indicates...

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Main Authors: Pangilinan, Faith, Geiler, Kerry, Dolle, Jessica, Troendle, James, Swanson, Deborah A., Molloy, Anne M., Sutton, Marie, Conley, Mary, Kirke, Peadar N., Scott, John M., Mills, James L., Brody, Lawrence C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836760/
https://ncbi.nlm.nih.gov/pubmed/18798306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.32504
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