Human immunodeficiency virus type 1 envelope glycoprotein molecules containing membrane fusion-impairing mutations in the V3 region efficiently undergo soluble CD4-stimulated gp120 release.

The ability of soluble forms of CD4 to induce gp120 release from the human immunodeficiency virus type 1 envelope glycoprotein complex may reflect molecular events associated with membrane fusion. The third hypervariable (V3) region of gp120 appears to play a role in fusion independent of CD4 bindin...

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Enregistré dans:
Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Berger, E A, Sisler, J R, Earl, P L
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283674/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1527858/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.10.6208-6212.1992
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