Human immunodeficiency virus type 1 envelope glycoprotein molecules containing membrane fusion-impairing mutations in the V3 region efficiently undergo soluble CD4-stimulated gp120 release.

The ability of soluble forms of CD4 to induce gp120 release from the human immunodeficiency virus type 1 envelope glycoprotein complex may reflect molecular events associated with membrane fusion. The third hypervariable (V3) region of gp120 appears to play a role in fusion independent of CD4 bindin...

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Main Authors: Berger, E A, Sisler, J R, Earl, P L
格式: Artigo
語言:Inglês
出版: 1992
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC283674/
https://ncbi.nlm.nih.gov/pubmed/1527858
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