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Nuclear location of an endogenously expressed antigen, EBNA1, restricts access to macroautophagy and the range of CD4 epitope display

Whereas exogenously acquired proteins are the major source of antigens feeding the MHC class II pathway in antigen-presenting cells, some endogenously expressed antigens also access that pathway but the rules governing such access are poorly understood. Here we address this using Epstein–Barr virus...

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Bibliografische gegevens
Hoofdauteurs: Leung, Carol S., Haigh, Tracey A., Mackay, Laura K., Rickinson, Alan B., Taylor, Graham S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836662/
https://ncbi.nlm.nih.gov/pubmed/20133861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909448107
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