Rescue of defective G protein–coupled receptor function in vivo by intermolecular cooperation

G protein–coupled receptors (GPCRs) are ubiquitous mediators of signaling of hormones, neurotransmitters, and sensing. The old dogma is that a one ligand/one receptor complex constitutes the functional unit of GPCR signaling. However, there is mounting evidence that some GPCRs form dimers or oligome...

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Bibliografiska uppgifter
Huvudupphovsmän: Rivero-Müller, Adolfo, Chou, Yen-Yin, Ji, Inhae, Lajic, Svetlana, Hanyaloglu, Aylin C., Jonas, Kim, Rahman, Nafis, Ji, Tae H., Huhtaniemi, Ilpo
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836644/
https://ncbi.nlm.nih.gov/pubmed/20080658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906695106
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