BONE MORPHOGENIC PROTEIN 2 DIRECTLY ENHANCES DIFFERENTIATION OF MURINE OSTEOCLAST PRECURSORS

Previous studies found that BMPs support osteoclast formation, but it is not clear whether this is a direct effect on osteoclasts or mediated indirectly through osteoblasts. We have shown that a mouse deficient for the BMP antagonist Twisted gastrulation suggested a direct positive role for BMPs on...

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Bibliographic Details
Main Authors: Jensen, Eric D, Pham, Lan, Billington, Charles J, Espe, Kelly, Carlson, Ann E, Westendorf, Jennifer J, Petryk, Anna, Gopalakrishnan, Rajaram, Mansky, Kim
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836597/
https://ncbi.nlm.nih.gov/pubmed/20039313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.22462
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