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Computing folding pathways between RNA secondary structures
Given an RNA sequence and two designated secondary structures A, B, we describe a new algorithm that computes a nearly optimal folding pathway from A to B. The algorithm, RNAtabupath, employs a tabu semi-greedy heuristic, known to be an effective search strategy in combinatorial optimization. Foldin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2836545/ https://ncbi.nlm.nih.gov/pubmed/20044352 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp1054 |
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