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E2F-1 has dual roles depending on the cell cycle

The E2F family of transcription factors play a critical role in the control of cell proliferation. E2F-1 is the major cellular target of pRB and is regulated by pRB during cell proliferation. E2F-1-mediated activation and repression of target genes occurs in different settings. The role of E2F-1 and...

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Autors principals: Sahin, Fikret, Sladek, Todd L.
Format: Artigo
Idioma:Inglês
Publicat: Ivyspring International Publisher 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836542/
https://ncbi.nlm.nih.gov/pubmed/20224733
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