Exogenous and endogenous ceramides elicit volume-sensitive chloride current in ventricular myocytes

AIMS: Because ceramide accumulates in several forms of cardiovascular disease and ceramide-induced apoptosis may involve the volume-sensitive Cl(−) current, I(Cl,swell), we assessed whether ceramide activates I(Cl,swell). METHODS AND RESULTS: I(Cl,swell) was measured in rabbit ventricular myocytes b...

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Main Authors: Raucci, Frank J., Wijesinghe, Dayanjan S., Chalfant, Charles E., Baumgarten, Clive M.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2010
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836262/
https://ncbi.nlm.nih.gov/pubmed/20008476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp399
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