Mitochondrial DNA Variants in the Pathogenesis of Type 2 Diabetes - Relevance of Asian Population Studies

Mitochondrial dysfunction involves defective insulin secretion by pancreatic beta-cells, and insulin resistance in insulin-sensitive tissues such as muscle and adipose tissue. Mitochondria are recognized as the most important cellular source of energy, and the major generator of intracellular reacti...

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Bibliographic Details
Main Authors: Wang, Pei-Wen, Lin, Tsu-Kung, Weng, Shao-Wen, Liou, Chia-Wei
Format: Artigo
Language:Inglês
Published: SBDR - Society for Biomedical Diabetes Research 2009
Subjects:
Review
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836195/
https://ncbi.nlm.nih.gov/pubmed/20043036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1900/RDS.2009.6.237
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