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Tumor Resistance Explained by Hormesis

Enhanced drug (GDC 0449) resistance in a mouse model for human medulloblastoma is shown in the present paper to act via an hormetic response. This has significant implications, imposing constraints on the quantitative features of the dose response of the chemotherapeutic agent, affecting optimal stu...

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Detalhes bibliográficos
Main Authors: Calabrese, Edward J., Nascarella, Marc A.
Formato: Artigo
Idioma:Inglês
Publicado em: International Hormesis Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836143/
https://ncbi.nlm.nih.gov/pubmed/20221296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2203/dose-response.09-063.Calabrese
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