Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice

Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor, which controls adipocyte differentiation. We targeted with homologous recombination the PPARγ2-specific exon B, resulting in a white adipose tissue knockdown of PPARγ. Although homozygous (PPARγ(hyp/hyp)) mice are born with...

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Detaylı Bibliyografya
Asıl Yazarlar: Koutnikova, Hana, Cock, Terrie-Anne, Watanabe, Mitsuhiro, Houten, Sander M., Champy, Marie-France, Dierich, Andrée, Auwerx, Johan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2003
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC283613/
https://ncbi.nlm.nih.gov/pubmed/14603033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2336090100
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