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Compensation by the muscle limits the metabolic consequences of lipodystrophy in PPARγ hypomorphic mice
Peroxisome proliferator-activated receptor γ (PPARγ) is a nuclear receptor, which controls adipocyte differentiation. We targeted with homologous recombination the PPARγ2-specific exon B, resulting in a white adipose tissue knockdown of PPARγ. Although homozygous (PPARγ(hyp/hyp)) mice are born with...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2003
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC283613/ https://ncbi.nlm.nih.gov/pubmed/14603033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2336090100 |
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