Phospholipase C-related but Catalytically Inactive Protein Is Required for Insulin-induced Cell Surface Expression of γ-Aminobutyric Acid Type A Receptors

The γ-aminobutyric acid type A (GABA(A)) receptors play a pivotal role in fast synaptic inhibition in the central nervous system. One of the key factors for determining synaptic strength is the number of receptors on the postsynaptic membrane, which is maintained by the balance between cell surface...

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Main Authors: Fujii, Makoto, Kanematsu, Takashi, Ishibashi, Hitoshi, Fukami, Kiyoko, Takenawa, Tadaomi, Nakayama, Keiichi I., Moss, Stephen J., Nabekura, Junichi, Hirata, Masato
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836089/
https://ncbi.nlm.nih.gov/pubmed/19996098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.070045
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