Cerebrospinal Fluid Steroidomics: Are Bioactive Bile Acids Present in Brain?

In this study we have profiled the free sterol content of cerebrospinal fluid by a combination of charge tagging and liquid chromatography-tandem mass spectrometry. Surprisingly, the most abundant cholesterol metabolites were found to be C(27) and C(24) intermediates of the bile acid biosynthetic pa...

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Detalhes bibliográficos
Main Authors: Ogundare, Michael, Theofilopoulos, Spyridon, Lockhart, Andrew, Hall, Leslie J., Arenas, Ernest, Sjövall, Jan, Brenton, A. Gareth, Wang, Yuqin, Griffiths, William J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Lipids
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836072/
https://ncbi.nlm.nih.gov/pubmed/19996111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.086678
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