Uncoupling of Inflammation and Insulin Resistance by NF-κB in Transgenic Mice through Elevated Energy Expenditure

To study the metabolic activity of NF-κB, we investigated phenotypes of two different mouse models with elevated NF-κB activities. The transcriptional activity of NF-κB is enhanced either by overexpression of NF-κB p65 (RelA) in aP2-p65 mice or inactivation of NF-κB p50 (NF-κB1) through gene knock-o...

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Detalhes bibliográficos
Main Authors: Tang, Tianyi, Zhang, Jin, Yin, Jun, Staszkiewicz, Jaroslaw, Gawronska-Kozak, Barbara, Jung, Dae Young, Ko, Hwi Jin, Ong, Helena, Kim, Jason K., Mynatt, Randy, Martin, Roy J., Keenan, Michael, Gao, Zhanguo, Ye, Jianping
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836069/
https://ncbi.nlm.nih.gov/pubmed/20018865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.068007
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