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Reactive Oxygen Generated by NADPH Oxidase 1 (Nox1) Contributes to Cell Invasion by Regulating Matrix Metalloprotease-9 Production and Cell Migration

A mediating role of the reactive oxygen species-generating enzyme Nox1 has been suggested for Ras oncogene transformation phenotypes including anchorage-independent cell growth, augmented angiogenesis, and tumorigenesis. However, little is known about whether Nox1 signaling regulates cell invasivene...

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Bibliographische Detailangaben
Hauptverfasser: Shinohara, Masahiro, Adachi, Yoshifumi, Mitsushita, Junji, Kuwabara, Mitsuhiro, Nagasawa, Atsushi, Harada, Saori, Furuta, Shuichi, Zhang, Yugen, Seheli, Kajla, Miyazaki, Hitoshi, Kamata, Tohru
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836054/
https://ncbi.nlm.nih.gov/pubmed/20018867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.071779
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