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Human T Cell Lymphotropic Virus 1 Manipulates Interferon Regulatory Signals by Controlling the TAK1-IRF3 and IRF4 Pathways

We previously reported that human T cell lymphotropic virus 1 (HTLV-1) Tax oncoprotein constitutively activates transforming growth factor-β-activated kinase 1 (TAK1). Here, we established Tax-positive HuT-102 cells stably transfected with a short hairpin RNA vector (HuT-shTAK1 cells) and investigat...

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Dettagli Bibliografici
Autori principali: Suzuki, Shunsuke, Zhou, Yue, Refaat, Alaa, Takasaki, Ichiro, Koizumi, Keiichi, Yamaoka, Shoji, Tabuchi, Yoshiaki, Saiki, Ikuo, Sakurai, Hiroaki
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836049/
https://ncbi.nlm.nih.gov/pubmed/19955181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.031476
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