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Zileuton, a new efficient and safe systemic anti-acne drug

Tissue inflammation is a major component of the acne process. Leukotriene B(4) (LTB(4)) is considered to be a major player in the development of tissue inflammation. Synthesis of LTB(4) is controlled by the enzyme 5-lipoxygenase. Since Zileuton blocks the activity of 5-lipoxygenase, experimental and...

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Bibliographic Details
Main Author: Zouboulis, Christos C
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835912/
https://ncbi.nlm.nih.gov/pubmed/20436887
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