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Clinical physiology and mechanism of dizocilpine (MK-801): Electron transfer, radicals, redox metabolites and bioactivity

Dizocilpine (MK-801), an extensively investigated drug possessing secondary amine and benzenoid functions, displays a wide array of biological properties, including anticonvulsant and anesthetic. There is scant discussion of biomechanism. A relevant, important finding is formation of oxidative metab...

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Bibliografski detalji
Glavni autori: Kovacic, Peter, Somanathan, Ratnasamy
Format: Artigo
Jezik:Inglês
Izdano: Landes Bioscience 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835885/
https://ncbi.nlm.nih.gov/pubmed/20716924
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