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Ultrafast dynamics of diatomic ligand binding to nitrophorin 4

Nitrophorin 4 (NP4) is a heme protein that stores and delivers nitric oxide (NO) through pH sensitive conformational change. This protein uses the ferric state of a highly ruffled heme to bind NO tightly at low pH and release it at high pH. In this work, the rebinding kinetics of NO and CO to NP4 ar...

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Detalhes bibliográficos
Main Authors: Benabbas, Abdelkrim, Ye, Xiong, Kubo, Minoru, Zhang, Zhenyu, Maes, Estelle M., Montfort, William R., Champion, Paul M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835772/
https://ncbi.nlm.nih.gov/pubmed/20121274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja910005b
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