Discovery of Novel MicroRNAs in Female Reproductive Tract Using Next Generation Sequencing

MicroRNAs (miRNAs) are small non-coding RNAs that mediate post-transcriptional gene silencing. Over 700 human miRNAs have currently been identified, many of which are mutated or de-regulated in diseases. Here we report the identification of novel miRNAs through deep sequencing the small RNAome (<...

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Detalhes bibliográficos
Main Authors: Creighton, Chad J., Benham, Ashley L., Zhu, Huifeng, Khan, Mahjabeen F., Reid, Jeffrey G., Nagaraja, Ankur K., Fountain, Michael D., Dziadek, Olivia, Han, Derek, Ma, Lang, Kim, Jong, Hawkins, Shannon M., Anderson, Matthew L., Matzuk, Martin M., Gunaratne, Preethi H.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835764/
https://ncbi.nlm.nih.gov/pubmed/20224791
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009637
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