Neoadjuvant multidrug chemotherapy including High-Dose Methotrexate modifies VEGF expression in Osteosarcoma: an immunohistochemical analysis

BACKGROUND: Angiogenesis plays a role in the progression of osteosarcoma, as well as in other mesenchymal tumors and carcinomas, and it is most commonly assessed by vascular endothelial growth factor (VEGF) expression or tumor CD31-positive microvessel density (MVD). Tumor VEGF expression is predict...

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Hlavní autoři: Rossi, Barbara, Schinzari, Giovanni, Maccauro, Giulio, Scaramuzzo, Laura, Signorelli, Diego, Rosa, Michele A, Fabbriciani, Carlo, Carlo, Barone
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835659/
https://ncbi.nlm.nih.gov/pubmed/20158913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-11-34
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