Neoadjuvant multidrug chemotherapy including High-Dose Methotrexate modifies VEGF expression in Osteosarcoma: an immunohistochemical analysis

BACKGROUND: Angiogenesis plays a role in the progression of osteosarcoma, as well as in other mesenchymal tumors and carcinomas, and it is most commonly assessed by vascular endothelial growth factor (VEGF) expression or tumor CD31-positive microvessel density (MVD). Tumor VEGF expression is predict...

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Bibliografiske detaljer
Main Authors: Rossi, Barbara, Schinzari, Giovanni, Maccauro, Giulio, Scaramuzzo, Laura, Signorelli, Diego, Rosa, Michele A, Fabbriciani, Carlo, Carlo, Barone
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2010
Fag:
Research article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835659/
https://ncbi.nlm.nih.gov/pubmed/20158913
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2474-11-34
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