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MUC4 Mucin Interacts with and Stabilizes the HER2 Oncoprotein in Human Pancreatic Cancer Cells

MUC4, a high–molecular weight transmembrane glycoprotein, is overexpressed in pancreatic cancer and is implicated in its pathogenesis. It is a heterodimeric protein containing a large extracellular, heavily glycosylated subunit, MUC4α, and a transmembrane growth factor–like subunit, MUC4β. In the pr...

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Detalhes bibliográficos
Main Authors: Chaturvedi, Pallavi, Singh, Ajay P., Chakraborty, Subhankar, Chauhan, Subhash C., Bafna, Sangeeta, Meza, Jane L., Singh, Pankaj K., Hollingsworth, Michael A., Mehta, Parmender P., Batra, Surinder K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835497/
https://ncbi.nlm.nih.gov/pubmed/18381409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6041
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