Redox susceptibility of SOD1 mutants is associated with the differential response to CCS over-expression in vivo

Over-expression of CCS in G93A SOD1 mice accelerates neurological disease and enhances mitochondrial pathology. We studied the effect of CCS over-expression in transgenic mice expressing G37R, G86R or L126Z SOD1 mutations in order to understand factors which influence mitochondrial dysfunction. Over...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Son, Marjatta, Fu, Qiao, Puttaparthi, Krishna, Matthews, Christina M., Elliott, Jeffrey L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835407/
https://ncbi.nlm.nih.gov/pubmed/19320055
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky