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Exceptionally High Payload of Doxorubicin in Hollow Gold Nanospheres for Near-Infrared Light-Triggered Drug Release

We report dual-functional hollow gold nanospheres (HAuNS, ∼40-nm diameter) capable of mediating both photothermal ablation of cancer cells and drug release upon near-infrared (NIR) light irradiation. As high as 63% DOX by weight (∼1.7 μg DOX/μg Au) could be loaded to polyethylene glycol (PEG)-coated...

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Autores principales: You, Jian, Zhang, Guodong, Li, Chun
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835401/
https://ncbi.nlm.nih.gov/pubmed/20121065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn901181c
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