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Fluid Phase Endocytosis Contributes to Transfection of DNA by PEI-25
The understanding of internalization pathways of lipo- or polyplexes is crucial for engineering successful reagents for nonviral gene transfection. A known inhibitor of fluid phase endocytosis (FPE), rottlerin, was used to quantify the contribution of this pathway by flow cytometric and fluorescence...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2835228/ https://ncbi.nlm.nih.gov/pubmed/19532143 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.121 |
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