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Sleeping Beauty Transposition From Nonintegrating Lentivirus

Lentiviral vectors enter cells with high efficiency and deliver stable transduction through integration into host chromosomes, but their preference for integration within actively transcribing genes means that insertional mutagenesis following disruption of host proto-oncogenes is a recognized conce...

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Detalhes bibliográficos
Main Authors: Vink, Conrad A, Gaspar, H Bobby, Gabriel, Richard, Schmidt, Manfred, McIvor, R Scott, Thrasher, Adrian J, Qasim, Waseem
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835211/
https://ncbi.nlm.nih.gov/pubmed/19417741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.94
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