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Adoptive Transfer of Human Papillomavirus E7-specific CTL Enhances Tumor Chemoresponse Through the Perforin/Granzyme-mediated Pathway

Adoptive cytotoxic T lymphocyte (CTL) therapy has an important implication in treating cancer patients. Here, we investigate whether adoptive transfer of human papillomavirus (HPV) E7-specific CTL can enhance tumor chemoresponse using an established cervical cancer animal model. Cisplatin-based chem...

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Detalhes bibliográficos
Main Authors: Sin, Jeong-Im, Kim, Jung-Min, Bae, Sung Hwa, Lee, In Hee, Park, Jong Sup, Ryoo, Hun Mo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835135/
https://ncbi.nlm.nih.gov/pubmed/19277009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.32
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