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Spermidine but not spermine is essential for hypusine biosynthesis and growth in Saccharomyces cerevisiae: Spermine is converted to spermidine in vivo by the FMS1-amine oxidase

In our earlier work we showed that either spermidine or spermine could support the growth of spe2Δ or spe3Δ polyamine-requiring mutants, but it was unclear whether the cells had a specific requirement for either of these amines. In the current work, we demonstrate that spermidine is specifically req...

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Autors principals: Chattopadhyay, Manas K., Tabor, Celia White, Tabor, Herbert
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC283513/
https://ncbi.nlm.nih.gov/pubmed/14617780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1835918100
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