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Transgene Expression Levels Determine the Immunogenicity of Transduced Hematopoietic Grafts in Partially Myeloablated Mice

We investigated whether transgene expression levels influence the immunogenicity of transduced hematopoietic grafts upon transplantation into partially myeloablated mice. To this aim, bone marrow cells (BMCs) transduced with retroviral vectors driving green fluorescent protein (GFP) expression eithe...

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Detalhes bibliográficos
Main Authors: Eixarch, Herena, Gómez, Alba, Kádár, Elisabeth, George, Mónica, Martínez, Nuria, Espejo, Carmen, Pétriz, Jordi, Gimeno, Ramon, Barquinero, Jordi
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2835042/
https://ncbi.nlm.nih.gov/pubmed/19707185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2009.198
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