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Transplantation of PC1/3-Expressing α-cells Improves Glucose Handling and Cold Tolerance in Leptin-resistant Mice

Type 2 diabetes (T2D) is characterized by elevated blood glucose levels owing to insufficient secretion and/or activity of the glucose-lowering hormone insulin. Glucagon-like peptide-1 (GLP-1) has received much attention as a new treatment for diabetes because of its multiple blood glucose–lowering...

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Detalhes bibliográficos
Main Authors: Wideman, Rhonda D, Gray, Sarah L, Covey, Scott D, Webb, Gene C, Kieffer, Timothy J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834990/
https://ncbi.nlm.nih.gov/pubmed/18941442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2008.219
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