Microfabricated needles for transdermal delivery of macromolecules and nanoparticles: Fabrication methods and transport studies

Arrays of micrometer-scale needles could be used to deliver drugs, proteins, and particles across skin in a minimally invasive manner. We therefore developed microfabrication techniques for silicon, metal, and biodegradable polymer microneedle arrays having solid and hollow bores with tapered and be...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	McAllister, Devin V., Wang, Ping M., Davis, Shawn P., Park, Jung-Hwan, Canatella, Paul J., Allen, Mark G., Prausnitz, Mark R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2003
Assuntos:	Physical Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC283494/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14623977/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.2331316100
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