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Pilot Study of Pentoxifylline in Hepatopulmonary Syndrome

Hepatopulmonary syndrome (HPS) results when chronic liver disease or portal hypertension causes intrapulmonary microvascular dilatation with hypoxemia. In experimental HPS, tumor necrosis factor alpha (TNF-α) overproduction contributes to vasodilatation, which is improved by pentoxifylline, a TNF-α...

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Bibliographic Details
Main Authors: Tanikella, Rajasekhar, Philips, George M., Faulk, Dorothy K., Kawut, Steven M., Fallon, Michael B.
Format: Artigo
Language:Inglês
Published: 2008
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834782/
https://ncbi.nlm.nih.gov/pubmed/18668653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/lt.21482
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