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Suppressive and additive effects in protection mediated by combinations of monoclonal antibodies specific for merozoite surface protein 1 of Plasmodium yoelii

BACKGROUND: The merozoite surface protein (MSP)-1 is a target antigen of protective immunity and a malaria vaccine candidate. The nature of this protective immune response warrants further investigation: although specific antibody is thought to play a major role, the mechanisms of protection are sti...

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Detalhes bibliográficos
Main Authors: Eslava, Irosoki, Payares, Gilberto, Pernia, Beatriz M, Holder, Anthony A, Spencer, Lilian M
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834700/
https://ncbi.nlm.nih.gov/pubmed/20146804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2875-9-46
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