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Lineage-specific co-evolution of the Egf receptor/ligand signaling system

BACKGROUND: The epidermal growth factor receptor (Egfr) with its numerous ligands has fundamental roles in development, cell differentiation and physiology. Dysfunction of the receptor-ligand system contributes to many human malignancies. Consistent with such various tasks, the Egfr gene family has...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Laisney, Juliette AGC, Braasch, Ingo, Walter, Ronald B, Meierjohann, Svenja, Schartl, Manfred
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834686/
https://ncbi.nlm.nih.gov/pubmed/20105326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2148-10-27
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