Insulin-like growth factor binding protein 5 enhances survival of LX2 human hepatic stellate cells

BACKGROUND: Expression of insulin-like growth factor binding protein 5 (IGFBP5) is strongly induced upon activation of hepatic stellate cells and their transdifferentiation into myofibroblasts in vitro. This was confirmed in vivo in an animal model of liver fibrosis. Since IGFBP5 has been shown to p...

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Hlavní autoři: Sokolović, Aleksandar, Sokolović, Milka, Boers, Willem, Elferink, Ronald PJ Oude, Bosma, Piter J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2010
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2834615/
https://ncbi.nlm.nih.gov/pubmed/20163708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-3-3
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